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Analysis of the retinal gene expression profile after hypoxic preconditioning identifies candidate genes for neuroprotection

BACKGROUND: Retinal degeneration is a main cause of blindness in humans. Neuroprotective therapies may be used to rescue retinal cells and preserve vision. Hypoxic preconditioning stabilizes the transcription factor HIF-1α in the retina and strongly protects photoreceptors in an animal model of ligh...

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Detalles Bibliográficos
Autores principales: Thiersch, Markus, Raffelsberger, Wolfgang, Frigg, Rico, Samardzija, Marijana, Wenzel, Andreas, Poch, Olivier, Grimm, Christian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270833/
https://www.ncbi.nlm.nih.gov/pubmed/18261226
http://dx.doi.org/10.1186/1471-2164-9-73