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Augmented serum level of major histocompatibility complex class I-related chain A (MICA) protein and reduced NKG2D expression on NK and T cells in patients with cervical cancer and precursor lesions

BACKGROUND: Cervical cancer is the second most common cancer in women worldwide. NK and cytotoxic T cells play an important role in the elimination of virus-infected and tumor cells through NKG2D activating receptors, which can promote the lysis of target cells by binding to the major histocompatibi...

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Detalles Bibliográficos
Autores principales: Arreygue-Garcia, Naela A, Daneri-Navarro, Adrian, del Toro-Arreola, Alicia, Cid-Arregui, Angel, Gonzalez-Ramella, Oscar, Jave-Suarez, Luis F, Aguilar-Lemarroy, Adriana, Troyo-Sanroman, Rogelio, Bravo-Cuellar, Alejandro, Delgado-Rizo, Vidal, Garcia-Iglesias, Trinidad, Hernandez-Flores, Georgina, del Toro-Arreola, Susana
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270854/
https://www.ncbi.nlm.nih.gov/pubmed/18208618
http://dx.doi.org/10.1186/1471-2407-8-16