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Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

Tumor necrosis factor (TNF) is key to the pathogenesis of various arthritic diseases and inflammatory bowel disease (IBD). Anti-TNF therapies have proved successful in the clinical treatment of these diseases, but a mechanistic understanding of TNF function is still lacking. We have investigated ear...

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Detalles Bibliográficos
Autores principales: Armaka, Maria, Apostolaki, Maria, Jacques, Peggy, Kontoyiannis, Dimitris L., Elewaut, Dirk, Kollias, George
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271010/
https://www.ncbi.nlm.nih.gov/pubmed/18250193
http://dx.doi.org/10.1084/jem.20070906