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Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases
Tumor necrosis factor (TNF) is key to the pathogenesis of various arthritic diseases and inflammatory bowel disease (IBD). Anti-TNF therapies have proved successful in the clinical treatment of these diseases, but a mechanistic understanding of TNF function is still lacking. We have investigated ear...
Autores principales: | Armaka, Maria, Apostolaki, Maria, Jacques, Peggy, Kontoyiannis, Dimitris L., Elewaut, Dirk, Kollias, George |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271010/ https://www.ncbi.nlm.nih.gov/pubmed/18250193 http://dx.doi.org/10.1084/jem.20070906 |
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