Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease

From the inoculation of Plasmodium sporozoites via Anopheles mosquito bites to the development of blood-stage parasites, a hallmark of the host response is an inflammatory reaction characterized by elevated histamine levels in the serum and tissues. Given the proinflammatory and immunosuppressive ac...

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Detalles Bibliográficos
Autores principales: Beghdadi, Walid, Porcherie, Adeline, Schneider, Bradley S., Dubayle, David, Peronet, Roger, Huerre, Michel, Watanabe, Takeshi, Ohtsu, Hiroshi, Louis, Jacques, Mécheri, Salaheddine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271011/
https://www.ncbi.nlm.nih.gov/pubmed/18227221
http://dx.doi.org/10.1084/jem.20071548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271011/
https://www.ncbi.nlm.nih.gov/pubmed/18227221
http://dx.doi.org/10.1084/jem.20071548

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