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Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease
From the inoculation of Plasmodium sporozoites via Anopheles mosquito bites to the development of blood-stage parasites, a hallmark of the host response is an inflammatory reaction characterized by elevated histamine levels in the serum and tissues. Given the proinflammatory and immunosuppressive ac...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271011/ https://www.ncbi.nlm.nih.gov/pubmed/18227221 http://dx.doi.org/10.1084/jem.20071548 |