Targeted inactivation of the COP9 signalosome impairs multiple stagesof T cell development

Genetic programs promoting cell cycle progression, DNA repair, and survival are coordinately induced in developing T cells and require rapid turnover of effector molecules. As the COP9 signalosome (CSN) has been placed at the crossroads of these programs in lower organisms, we addressed its role by...

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Detalles Bibliográficos
Autores principales: Panattoni, Martina, Sanvito, Francesca, Basso, Veronica, Doglioni, Claudio, Casorati, Giulia, Montini, Eugenio, Bender, Jeffrey R., Mondino, Anna, Pardi, Ruggero
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271025/
https://www.ncbi.nlm.nih.gov/pubmed/18268034
http://dx.doi.org/10.1084/jem.20070725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271025/
https://www.ncbi.nlm.nih.gov/pubmed/18268034
http://dx.doi.org/10.1084/jem.20070725

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