Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20

Toll-like receptors (TLRs) on host cells are chronically engaged by microbial ligands during homeostatic conditions. These signals do not cause inflammatory immune responses in unperturbed mice, even though they drive innate and adaptive immune responses when combating microbial infections. A20 is a...

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Detalles Bibliográficos
Autores principales: Turer, Emre E., Tavares, Rita M., Mortier, Erwan, Hitotsumatsu, Osamu, Advincula, Rommel, Lee, Bettina, Shifrin, Nataliya, Malynn, Barbara A., Ma, Averil
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271029/
https://www.ncbi.nlm.nih.gov/pubmed/18268035
http://dx.doi.org/10.1084/jem.20071108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271029/
https://www.ncbi.nlm.nih.gov/pubmed/18268035
http://dx.doi.org/10.1084/jem.20071108

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