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Maternal Cocaine Administration in Mice Alters DNA Methylation and Gene Expression in Hippocampal Neurons of Neonatal and Prepubertal Offspring

Previous studies documented significant behavioral changes in the offspring of cocaine-exposed mothers. We now explore the hypothesis that maternal cocaine exposure could alter the fetal epigenetic machinery sufficiently to cause lasting neurochemical and functional changes in the offspring. Pregnan...

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Detalles Bibliográficos
Autores principales: Novikova, Svetlana I., He, Fang, Bai, Jie, Cutrufello, Nicholas J., Lidow, Michael S., Undieh, Ashiwel S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271055/
https://www.ncbi.nlm.nih.gov/pubmed/18382688
http://dx.doi.org/10.1371/journal.pone.0001919