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Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus

Alphavirus-based vector and replicon systems have been extensively used experimentally and are likely to be used in human and animal medicine. Whilst marker genes can be inserted easily under the control of a duplicated subgenomic promoter, these constructs are often genetically unstable. Here, a no...

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Detalles Bibliográficos
Autores principales: Tamberg, Nele, Lulla, Valeria, Fragkoudis, Rennos, Lulla, Aleksei, Fazakerley, John K., Merits, Andres
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2274952/
https://www.ncbi.nlm.nih.gov/pubmed/17374766
http://dx.doi.org/10.1099/vir.0.82436-0