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Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect
Tumor necrosis factor (TNF) initiates local inflammation by triggering endothelial cells (EC) to express adhesion molecules for leukocytes such as intercellular adhesion molecule-1 (ICAM-1 or CD54). A prior study identified siRNA molecules that reduce ICAM-1 expression in cultured human umbilical ve...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275081/ https://www.ncbi.nlm.nih.gov/pubmed/18096615 http://dx.doi.org/10.1093/nar/gkm630 |