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Inhibition of DNA replication fork progression and mutagenic potential of 1, N(6)-ethenoadenine and 8-oxoguanine in human cell extracts
Comparative mutagenesis of 1,N(6)-ethenoadenine (εA) and 8-oxoguanine (8-oxoG), two endogenous DNA lesions that are also formed by exogenous DNA damaging agents, have been evaluated in HeLa and xeroderma pigmentosum variant (XPV) cell extracts. Two-dimensional gel electrophoresis of the duplex M13mp...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275085/ https://www.ncbi.nlm.nih.gov/pubmed/18184697 http://dx.doi.org/10.1093/nar/gkm1157 |