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Inhibition of DNA replication fork progression and mutagenic potential of 1, N(6)-ethenoadenine and 8-oxoguanine in human cell extracts

Comparative mutagenesis of 1,N(6)-ethenoadenine (εA) and 8-oxoguanine (8-oxoG), two endogenous DNA lesions that are also formed by exogenous DNA damaging agents, have been evaluated in HeLa and xeroderma pigmentosum variant (XPV) cell extracts. Two-dimensional gel electrophoresis of the duplex M13mp...

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Detalles Bibliográficos
Autores principales: Tolentino, Joel H., Burke, Tom J., Mukhopadhyay, Suparna, McGregor, W. Glenn, Basu, Ashis K.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275085/
https://www.ncbi.nlm.nih.gov/pubmed/18184697
http://dx.doi.org/10.1093/nar/gkm1157

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