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DNA mimicry by a high-affinity anti-NF-κB RNA aptamer

The binding of RNA molecules to proteins or other ligands can require extensive RNA folding to create an induced fit. Understanding the generality of this principle involves comparing structures of RNA before and after complex formation. Here we report the NMR solution structure of a 29-nt RNA aptam...

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Detalles Bibliográficos
Autores principales: Reiter, Nicholas J., Maher, L. James, Butcher, Samuel E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275087/
https://www.ncbi.nlm.nih.gov/pubmed/18160411
http://dx.doi.org/10.1093/nar/gkm1141