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Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans

DNA repair is an important mechanism by which cells maintain genomic integrity. Decline in DNA repair capacity or defects in repair factors are thought to contribute to premature aging in mammals. The nematode Caenorhabditis elegans is a good model for studying longevity and DNA repair because of ke...

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Detalles Bibliográficos
Autores principales: Hyun, Moonjung, Lee, Jihyun, Lee, Kyungjin, May, Alfred, Bohr, Vilhelm A., Ahn, Byungchan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275101/
https://www.ncbi.nlm.nih.gov/pubmed/18203746
http://dx.doi.org/10.1093/nar/gkm1161