Chromatinized templates reveal the requirement for the LEDGF/p75 PWWP domain during HIV-1 integration in vitro

Integration is an essential step in the retroviral lifecycle, and the lentiviral integrase binding protein lens epithelium-derived growth factor (LEDGF)/p75 plays a crucial role during human immunodeficiency virus type 1 (HIV-1) cDNA integration. In vitro, LEDGF/p75 stimulates HIV-1 integrase activi...

Descripción completa

Detalles Bibliográficos
Autores principales: Botbol, Yaïr, Raghavendra, Nidhanapati K., Rahman, Shaila, Engelman, Alan, Lavigne, Marc
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275106/
https://www.ncbi.nlm.nih.gov/pubmed/18174227
http://dx.doi.org/10.1093/nar/gkm1127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275106/
https://www.ncbi.nlm.nih.gov/pubmed/18174227
http://dx.doi.org/10.1093/nar/gkm1127

Ejemplares similares