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Chromatinized templates reveal the requirement for the LEDGF/p75 PWWP domain during HIV-1 integration in vitro

Integration is an essential step in the retroviral lifecycle, and the lentiviral integrase binding protein lens epithelium-derived growth factor (LEDGF)/p75 plays a crucial role during human immunodeficiency virus type 1 (HIV-1) cDNA integration. In vitro, LEDGF/p75 stimulates HIV-1 integrase activi...

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Detalles Bibliográficos
Autores principales:	Botbol, Yaïr, Raghavendra, Nidhanapati K., Rahman, Shaila, Engelman, Alan, Lavigne, Marc
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275106/ https://www.ncbi.nlm.nih.gov/pubmed/18174227 http://dx.doi.org/10.1093/nar/gkm1127

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