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Predicting RNA-binding sites from the protein structure based on electrostatics, evolution and geometry
An RNA-binding protein places a surface helix, β-ribbon, or loop in an RNA helix groove and/or uses a cavity to accommodate unstacked bases. Hence, our strategy for predicting RNA-binding residues is based on detecting a surface patch and a disparate cleft. These were generated and scored according...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275128/ https://www.ncbi.nlm.nih.gov/pubmed/18276647 http://dx.doi.org/10.1093/nar/gkn008 |