Cargando…

Predicting RNA-binding sites from the protein structure based on electrostatics, evolution and geometry

An RNA-binding protein places a surface helix, β-ribbon, or loop in an RNA helix groove and/or uses a cavity to accommodate unstacked bases. Hence, our strategy for predicting RNA-binding residues is based on detecting a surface patch and a disparate cleft. These were generated and scored according...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yao Chi, Lim, Carmay
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275128/
https://www.ncbi.nlm.nih.gov/pubmed/18276647
http://dx.doi.org/10.1093/nar/gkn008