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Histone H1 functions as a stimulatory factor in backup pathways of NHEJ

DNA double-strand breaks (DSBs) induced in the genome of higher eukaryotes by ionizing radiation (IR) are predominantly removed by two pathways of non-homologous end-joining (NHEJ) termed D-NHEJ and B-NHEJ. While D-NHEJ depends on the activities of the DNA-dependent protein kinase (DNA-PK) and DNA l...

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Detalles Bibliográficos
Autores principales: Rosidi, Bustanur, Wang, Minli, Wu, Wenqi, Sharma, Aparna, Wang, Huichen, Iliakis, George
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275134/
https://www.ncbi.nlm.nih.gov/pubmed/18250087
http://dx.doi.org/10.1093/nar/gkn013