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Chiral introduction of positive charges to PNA for double-duplex invasion to versatile sequences

Invasion of two PNA strands to double-stranded DNA is one of the most promising methods to recognize a predetermined site in double-stranded DNA (PNA = peptide nucleic acid). In order to facilitate this ‘double-duplex invasion’, a new type of PNA was prepared by using chiral PNA monomers in which a...

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Detalles Bibliográficos
Autores principales: Ishizuka, Takumi, Yoshida, Junya, Yamamoto, Yoji, Sumaoka, Jun, Tedeschi, Tullia, Corradini, Roberto, Sforza, Stefano, Komiyama, Makoto
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275137/
https://www.ncbi.nlm.nih.gov/pubmed/18203747
http://dx.doi.org/10.1093/nar/gkm1154