Primary T-lymphocytes rescue the replication of HIV-1 DIS RNA mutants in part by facilitating reverse transcription

The dimerization initiation site (DIS) stem-loop within the HIV-1 RNA genome is vital for the production of infectious virions in T-cell lines but not in primary cells. In comparison to peripheral blood mononuclear cells (PBMCs), which can support the replication of both wild type and HIV-1 DIS RNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Kate L., Sonza, Secondo, Mak, Johnson
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275147/
https://www.ncbi.nlm.nih.gov/pubmed/18216043
http://dx.doi.org/10.1093/nar/gkm1149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275147/
https://www.ncbi.nlm.nih.gov/pubmed/18216043
http://dx.doi.org/10.1093/nar/gkm1149

Ejemplares similares