Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65

Nuclear factor kappaB (NF-κB) plays an important role in the transcriptional regulation of genes involved in immunity and cell survival. We show here in vitro and in vivo acetylation of RelA/p65 by p300 on lysine 314 and 315, two novel acetylation sites. Additionally, we confirmed the acetylation on...

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Detalles Bibliográficos
Autores principales: Buerki, Christine, Rothgiesser, Karin M., Valovka, Taras, Owen, Heather R., Rehrauer, Hubert, Fey, Monika, Lane, William S., Hottiger, Michael O.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275151/
https://www.ncbi.nlm.nih.gov/pubmed/18263619
http://dx.doi.org/10.1093/nar/gkn003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275151/
https://www.ncbi.nlm.nih.gov/pubmed/18263619
http://dx.doi.org/10.1093/nar/gkn003

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