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rRNA mutants in the yeast peptidyltransferase center reveal allosteric information networks and mechanisms of drug resistance

To ensure accurate and rapid protein synthesis, nearby and distantly located functional regions of the ribosome must dynamically communicate and coordinate with one another through a series of information exchange networks. The ribosome is ∼2/3 rRNA and information should pass mostly through this me...

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Detalles Bibliográficos
Autores principales: Rakauskaitė, Rasa, Dinman, Jonathan D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275155/
https://www.ncbi.nlm.nih.gov/pubmed/18203742
http://dx.doi.org/10.1093/nar/gkm1179