Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA

The tumour suppressor p53 is a transcription factor that binds DNA in the vicinity of the genes it controls. The affinity of p53 for specific binding sites relative to other DNA sequences is an inherent driving force for specificity, all other things being equal. We measured the binding affinities o...

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Detalles Bibliográficos
Autores principales: Veprintsev, Dmitry B., Fersht, Alan R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275157/
https://www.ncbi.nlm.nih.gov/pubmed/18234719
http://dx.doi.org/10.1093/nar/gkm1040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275157/
https://www.ncbi.nlm.nih.gov/pubmed/18234719
http://dx.doi.org/10.1093/nar/gkm1040

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