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Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA
The tumour suppressor p53 is a transcription factor that binds DNA in the vicinity of the genes it controls. The affinity of p53 for specific binding sites relative to other DNA sequences is an inherent driving force for specificity, all other things being equal. We measured the binding affinities o...
Autores principales: | Veprintsev, Dmitry B., Fersht, Alan R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275157/ https://www.ncbi.nlm.nih.gov/pubmed/18234719 http://dx.doi.org/10.1093/nar/gkm1040 |
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