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Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1)
The Krüppel-like zinc finger protein Gli-similar 3 (Glis3) plays a critical role in pancreatic development and has been implicated in a syndrome with neonatal diabetes and hypothyroidism (NDH). In this study, we examine three steps critical in the mechanism of the transcriptional regulation by Glis3...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275160/ https://www.ncbi.nlm.nih.gov/pubmed/18263616 http://dx.doi.org/10.1093/nar/gkn009 |