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Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1)

The Krüppel-like zinc finger protein Gli-similar 3 (Glis3) plays a critical role in pancreatic development and has been implicated in a syndrome with neonatal diabetes and hypothyroidism (NDH). In this study, we examine three steps critical in the mechanism of the transcriptional regulation by Glis3...

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Detalles Bibliográficos
Autores principales: Beak, Ju Youn, Kang, Hong Soon, Kim, Yong-Sik, Jetten, Anton M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275160/
https://www.ncbi.nlm.nih.gov/pubmed/18263616
http://dx.doi.org/10.1093/nar/gkn009