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Supervised Lowess normalization of comparative genome hybridization data – application to lactococcal strain comparisons

BACKGROUND: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less conserved genome sequences than eukaryotes, sequence divergences between the genes in the genomes used for an aCGH experiment...

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Detalles Bibliográficos
Autores principales: van Hijum, Sacha AFT, Baerends, Richard JS, Zomer, Aldert L, Karsens, Harma A, Martin-Requena, Victoria, Trelles, Oswaldo, Kok, Jan, Kuipers, Oscar P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275246/
https://www.ncbi.nlm.nih.gov/pubmed/18267014
http://dx.doi.org/10.1186/1471-2105-9-93