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A Bayesian Change point model for differential gene expression patterns of the DosR regulon of Mycobacterium tuberculosis

BACKGROUND: Low oxygen availability has been shown previously to stimulate M. tuberculosis to establish non-replicative persistence in vitro. The two component sensor/regulator dosRS is a major mediator in the transcriptional response of M. tuberculosis to hypoxia and controls a regulon of approxima...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Hatch, Kim A, Wernisch, Lorenz, Bacon, Joanna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275270/
https://www.ncbi.nlm.nih.gov/pubmed/18294384
http://dx.doi.org/10.1186/1471-2164-9-87