Cargando…

A Bayesian Change point model for differential gene expression patterns of the DosR regulon of Mycobacterium tuberculosis

BACKGROUND: Low oxygen availability has been shown previously to stimulate M. tuberculosis to establish non-replicative persistence in vitro. The two component sensor/regulator dosRS is a major mediator in the transcriptional response of M. tuberculosis to hypoxia and controls a regulon of approxima...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yi, Hatch, Kim A, Wernisch, Lorenz, Bacon, Joanna
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275270/ https://www.ncbi.nlm.nih.gov/pubmed/18294384 http://dx.doi.org/10.1186/1471-2164-9-87

Ejemplares similares

An integrated machine learning approach for predicting DosR-regulated genes in Mycobacterium tuberculosis
por: Zhang, Yi, et al.
Publicado: (2010)

Mycobacterium tuberculosis Growth following Aerobic Expression of the DosR Regulon
por: Minch, Kyle, et al.
Publicado: (2012)

Comprehensive insights into Mycobacterium tuberculosis DevR (DosR) regulon activation switch
por: Chauhan, Santosh, et al.
Publicado: (2011)

Mycobacterium tuberculosis DosS binds H(2)S through its Fe(3+) heme iron to regulate the DosR dormancy regulon
por: Sevalkar, Ritesh R., et al.
Publicado: (2022)

Significant under expression of the DosR regulon in M. tuberculosis complex lineage 6 in sputum
por: Ofori-Anyinam, Boatema, et al.
Publicado: (2017)

Mycobacterium tuberculosis DosR Regulon Gene Rv0079 Encodes a Putative, ‘Dormancy Associated Translation Inhibitor (DATIN)’
por: Kumar, Ashutosh, et al.
Publicado: (2012)

Lysine acetylation of DosR regulates the hypoxia response of Mycobacterium tuberculosis
por: Yang, Hua, et al.
Publicado: (2018)

Mycobacterium tuberculosis sensor kinase DosS modulates the autophagosome in a DosR-independent manner
por: Gautam, Uma S., et al.
Publicado: (2019)

The DosS-DosT/DosR Mycobacterial Sensor System
por: Sivaramakrishnan, Santhosh, et al.
Publicado: (2013)

A putative nitroreductase from the DosR regulon of Mycobacterium tuberculosis induces pro-inflammatory cytokine expression via TLR2 signaling pathway
por: Peddireddy, Vidyullatha, et al.
Publicado: (2016)

Novel vaccine potential of Rv3131, a DosR regulon-encoded putative nitroreductase, against hyper-virulent Mycobacterium tuberculosis strain K
por: Kwon, Kee Woong, et al.
Publicado: (2017)

Mycobacterium abscessus DosRS two-component system controls a species-specific regulon required for adaptation to hypoxia
por: Simcox, Breven S., et al.
Publicado: (2023)

Mycobacterium tuberculosis DosR Regulon Gene Rv2004c Encodes a Novel Antigen with Pro-inflammatory Functions and Potential Diagnostic Application for Detection of Latent Tuberculosis
por: Doddam, Sankara Narayana, et al.
Publicado: (2017)

Expression, maturation and turnover of DrrS, an unusually stable, DosR regulated small RNA in Mycobacterium tuberculosis
por: Moores, Alexandra, et al.
Publicado: (2017)

Humoral Responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR Regulon-Encoded Proteins of Mycobacterium tuberculosis in Individuals with Latent Tuberculosis Infection
por: Kimuda, Simon G., et al.
Publicado: (2017)

Appropriate DevR (DosR)-Mediated Signaling Determines Transcriptional Response, Hypoxic Viability and Virulence of Mycobacterium tuberculosis
por: De Majumdar, Shyamasree, et al.
Publicado: (2012)

Mycobacterium tuberculosis DosR is Required for Activity of the P(mbtB) and P(mbtI) Promoters under Hypoxia
por: Schreuder, Lise J., et al.
Publicado: (2014)

Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence
por: Smith, Laura J., et al.
Publicado: (2017)

Mycobacterium tuberculosis DevR/DosR Dormancy Regulator Activation Mechanism: Dispensability of Phosphorylation, Cooperativity and Essentiality of α10 Helix
por: Sharma, Saurabh, et al.
Publicado: (2016)

Acetylation of lysine 182 inhibits the ability of Mycobacterium tuberculosis DosR to bind DNA and regulate gene expression during hypoxia
por: Bi, Jing, et al.
Publicado: (2018)

Potential of DosR and Rpf antigens from Mycobacterium tuberculosis to discriminate between latent and active tuberculosis in a tuberculosis endemic population of Medellin Colombia
por: Arroyo, Leonar, et al.
Publicado: (2018)

The Dormancy Regulator DosR Controls Ribosome Stability in Hypoxic Mycobacteria
por: Trauner, Andrej, et al.
Publicado: (2012)

Circulating Mycobacterium tuberculosis DosR latency antigen-specific, polyfunctional, regulatory IL10(+) Th17 CD4 T-cells differentiate latent from active tuberculosis
por: Rakshit, Srabanti, et al.
Publicado: (2017)

Identification and in silico functional prediction of lineage-specific SNPs distributed in DosR-related proteins and resuscitation-promoting factor proteins of Mycobacterium tuberculosis
por: Tantivitayakul, Pornpen, et al.
Publicado: (2020)

Characterization of a cAMP responsive transcription factor, Cmr (Rv1675c), in TB complex mycobacteria reveals overlap with the DosR (DevR) dormancy regulon
por: Ranganathan, Sridevi, et al.
Publicado: (2016)

DevR (DosR) mimetic peptides impair transcriptional regulation and survival of Mycobacterium tuberculosis under hypoxia by inhibiting the autokinase activity of DevS sensor kinase
por: Kaur, Kohinoor, et al.
Publicado: (2014)

The Copper-Responsive RicR Regulon Contributes to Mycobacterium tuberculosis Virulence
por: Shi, Xiaoshan, et al.
Publicado: (2014)

OsdR of Streptomyces coelicolor and the Dormancy Regulator DevR of Mycobacterium tuberculosis Control Overlapping Regulons
por: Urem, Mia, et al.
Publicado: (2016)

A comparison of machine learning and Bayesian modelling for molecular serotyping
por: Newton, Richard, et al.
Publicado: (2017)

Characterisation of the Mycobacterium tuberculosis alternative sigma factor SigG: Its operon and regulon()
por: Gaudion, Alison, et al.
Publicado: (2013)

Non-Replicating Mycobacterium tuberculosis Elicits a Reduced Infectivity Profile with Corresponding Modifications to the Cell Wall and Extracellular Matrix
por: Bacon, Joanna, et al.
Publicado: (2014)

Empirical Bayesian models for analysing molecular serotyping microarrays
por: Newton, Richard, et al.
Publicado: (2011)

Genome wide analysis of the complete GlnR nitrogen-response regulon in Mycobacterium smegmatis
por: Jenkins, Victoria A, et al.
Publicado: (2013)

A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis
por: Kendall, Sharon L, et al.
Publicado: (2007)

Comprehensive Definition of the SigH Regulon of Mycobacterium tuberculosis Reveals Transcriptional Control of Diverse Stress Responses
por: Sharp, Jared D., et al.
Publicado: (2016)

Global Analysis of the Regulon of the Transcriptional Repressor LexA, a Key Component of SOS Response in Mycobacterium tuberculosis
por: Smollett, Katherine L., et al.
Publicado: (2012)

The GlnR Regulon in Streptococcus mutans Is Differentially Regulated by GlnR and PmrA
por: Chen, Yi-Ywan M., et al.
Publicado: (2016)

The Heat Shock Response of Mycobacterium Tuberculosis: Linking Gene Expression, Immunology and Pathogenesis
por: Stewart, Graham R., et al.
Publicado: (2002)

The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis - insights for early bactericidal activity?
por: Pullan, Steven T., et al.
Publicado: (2016)

Regrowth of Mycobacterium tuberculosis Populations Exposed to Antibiotic Combinations Is Due to the Presence of Isoniazid and Not Bacterial Growth Rate
por: Hendon-Dunn, Charlotte L., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_hghuntvt9d9m01ih0cqphqaqm0