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Comparative genomic analysis and evolution of the T cell receptor loci in the opossum Monodelphis domestica

BACKGROUND: All jawed-vertebrates have four T cell receptor (TCR) chains: alpha (TRA), beta (TRB), gamma (TRG) and delta (TRD). Marsupials appear unique by having an additional TCR: mu (TRM). The evolutionary origin of TRM and its relationship to other TCR remain obscure, and is confounded by previo...

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Detalles Bibliográficos
Autores principales: Parra, Zuly E, Baker, Michelle L, Hathaway, Jennifer, Lopez, April M, Trujillo, Jonathan, Sharp, Alana, Miller, Robert D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275272/
https://www.ncbi.nlm.nih.gov/pubmed/18312668
http://dx.doi.org/10.1186/1471-2164-9-111