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Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron
BACKGROUND: Iron overload is associated with liver toxicity, cirrhosis, and hepatocellular carcinoma in humans. While most iron circulates in blood as transferrin-bound iron, non-transferrin-bound iron (NTBI) also becomes elevated and contributes to toxicity in the setting of iron overload. The mech...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275280/ https://www.ncbi.nlm.nih.gov/pubmed/18254965 http://dx.doi.org/10.1186/1471-230X-8-2 |