Cargando…

Tissue factor/FVIIa activates Bcl-2 and prevents doxorubicin-induced apoptosis in neuroblastoma cells

BACKGROUND: Tissue factor (TF) is a transmembrane protein that acts as a receptor for activated coagulation factor VII (FVIIa), initiating the coagulation cascade. Recent studies demonstrate that expression of tumor-derived TF also mediates intracellular signaling relevant to tumor growth and apopto...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Jun, Gu, Lubing, Zhu, Ningxi, Tang, Hao, Alvarado, Carlos S, Zhou, Muxiang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275284/
https://www.ncbi.nlm.nih.gov/pubmed/18325115
http://dx.doi.org/10.1186/1471-2407-8-69