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Tissue factor/FVIIa activates Bcl-2 and prevents doxorubicin-induced apoptosis in neuroblastoma cells

BACKGROUND: Tissue factor (TF) is a transmembrane protein that acts as a receptor for activated coagulation factor VII (FVIIa), initiating the coagulation cascade. Recent studies demonstrate that expression of tumor-derived TF also mediates intracellular signaling relevant to tumor growth and apopto...

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Detalles Bibliográficos
Autores principales:	Fang, Jun, Gu, Lubing, Zhu, Ningxi, Tang, Hao, Alvarado, Carlos S, Zhou, Muxiang
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275284/ https://www.ncbi.nlm.nih.gov/pubmed/18325115 http://dx.doi.org/10.1186/1471-2407-8-69

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