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Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus
The cytotoxicity of Semliki Forest virus (SFV) infection is caused partly by the non-structural protein nsP2, an essential component of the SFV replicase complex. Due to the presence of a nuclear localization signal (NLS), nsP2 also localizes in the nucleus of infected cells. The present study analy...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Society for General Microbiology
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275301/ https://www.ncbi.nlm.nih.gov/pubmed/18272758 http://dx.doi.org/10.1099/vir.0.83320-0 |