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Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus

The cytotoxicity of Semliki Forest virus (SFV) infection is caused partly by the non-structural protein nsP2, an essential component of the SFV replicase complex. Due to the presence of a nuclear localization signal (NLS), nsP2 also localizes in the nucleus of infected cells. The present study analy...

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Detalles Bibliográficos
Autores principales: Tamm, Kristi, Merits, Andres, Sarand, Inga
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275301/
https://www.ncbi.nlm.nih.gov/pubmed/18272758
http://dx.doi.org/10.1099/vir.0.83320-0