A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains

Cyclic nucleotides (cAMP and cGMP) regulate multiple intracellular processes and are thus of a great general interest for molecular and structural biologists. To study the allosteric mechanism of different cyclic nucleotide binding (CNB) domains, we compared cAMP-bound and cAMP-free structures (PKA,...

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Detalles Bibliográficos
Autores principales: Kornev, Alexandr P., Taylor, Susan S., Ten Eyck, Lynn F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275311/
https://www.ncbi.nlm.nih.gov/pubmed/18404204
http://dx.doi.org/10.1371/journal.pcbi.1000056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275311/
https://www.ncbi.nlm.nih.gov/pubmed/18404204
http://dx.doi.org/10.1371/journal.pcbi.1000056

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