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Effects of size and topology of DNA molecules on intracellular delivery with non-viral gene carriers

BACKGROUND: Efforts to improve the efficiency of non-viral gene delivery require a better understanding of delivery kinetics of DNA molecules into clinically relevant cells. Towards this goal, three DNA molecules were employed to investigate the effects of DNA properties on cellular delivery: a circ...

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Detalles Bibliográficos
Autores principales: Hsu, Charlie Yu Ming, Uludağ, Hasan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275331/
https://www.ncbi.nlm.nih.gov/pubmed/18312664
http://dx.doi.org/10.1186/1472-6750-8-23