Cargando…

Fixing DNA breaks during class switch recombination

Immunoglobulin (Ig) class switch recombination (CSR) involves the breakage and subsequent repair of two DNA sequences, known as switch (S) regions, which flank IgH constant region exons. The resolution of CSR-associated breaks is thought to require the nonhomologous end-joining (NHEJ) DNA repair pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jolly, Christopher J., Cook, Adam J.L., Manis, John P.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Commentaries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275374/ https://www.ncbi.nlm.nih.gov/pubmed/18332183 http://dx.doi.org/10.1084/jem.20080356

Ejemplares similares

The Function of AID in Somatic Mutation and Class Switch Recombination: Upstream or Downstream of DNA Breaks
por: Chua, Katrin F., et al.
Publicado: (2002)

Generating and repairing genetically programmed DNA breaks during immunoglobulin class switch recombination
por: Nicolas, Laura, et al.
Publicado: (2018)

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
por: Guikema, Jeroen E.J., et al.
Publicado: (2007)

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
por: Guikema, Jeroen E.J., et al.
Publicado: (2007)

Orientation-Specific Joining of AID-initiated DNA Breaks Promotes Antibody Class Switching
por: Dong, Junchao, et al.
Publicado: (2015)

DNA polymerase β is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination
por: Wu, Xiaoming, et al.
Publicado: (2007)

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4
por: Boboila, Cristian, et al.
Publicado: (2010)

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4
por: Boboila, Cristian, et al.
Publicado: (2013)

The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination
por: Chahwan, Richard, et al.
Publicado: (2012)

Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching
por: Bothmer, Anne, et al.
Publicado: (2013)

Non-canonical uracil processing in DNA gives rise to double-strand breaks and deletions: relevance to class switch recombination
por: Bregenhorn, Stephanie, et al.
Publicado: (2016)

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination
por: Rocha, Pedro P., et al.
Publicado: (2016)

Polζ ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability
por: Schenten, Dominik, et al.
Publicado: (2009)

53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function
por: Sundaravinayagam, Devakumar, et al.
Publicado: (2019)

DNA Polymerase η Is Involved in Hypermutation Occurring during Immunoglobulin Class Switch Recombination
por: Faili, Ahmad, et al.
Publicado: (2004)

Quantitative Regulation of Class Switch Recombination by Switch Region Transcription
por: Lee, Chung-Gi, et al.
Publicado: (2001)

Rad52 mediates class-switch DNA recombination to IgD
por: Xu, Yijiang, et al.
Publicado: (2022)

Immunoglobulin class-switch recombination deficiencies
por: Durandy, Anne, et al.
Publicado: (2012)

The Liaison of Isotype Class Switch and Mismatch Repair: An Illegitimate Affair
por: Kenter, Amy L.
Publicado: (1999)

AID function in somatic hypermutation and class switch recombination: AID function in somatic hypermutation and class switch recombination
por: Yu, Kefei
Publicado: (2022)

Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells
por: Hartlerode, Andrea J., et al.
Publicado: (2016)

Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination
por: Jeevan-Raj, Beena Patricia, et al.
Publicado: (2011)

Correction: Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells
por: Hartlerode, Andrea J., et al.
Publicado: (2016)

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination
por: Soulas-Sprauel, Pauline, et al.
Publicado: (2007)

Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance
por: Takata, Kei-ichi, et al.
Publicado: (2017)

Epigenetic Codes Programing Class Switch Recombination
por: Vaidyanathan, Bharat, et al.
Publicado: (2015)

NME proteins regulate class switch recombination
por: Zheng, Simin, et al.
Publicado: (2018)

Making ends meet in class switch recombination
por: Wu, Lizhen, et al.
Publicado: (2020)

Ground Breaking and Breaking Ground
Publicado: (2001)

Ikaros controls isotype selection during immunoglobulin class switch recombination
por: Sellars, MacLean, et al.
Publicado: (2009)

Class Switching in B Cells Lacking 3′ Immunoglobulin Heavy Chain Enhancers
por: Manis, John P., et al.
Publicado: (1998)

Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination
por: Du, Likun, et al.
Publicado: (2008)

Processing of Switch Transcripts Is Required for Targeting of Antibody Class Switch Recombination
por: Hein, Katharina, et al.
Publicado: (1998)

Breaking microaggressions without breaking ourselves
por: Sukhera, Javeed
Publicado: (2019)

Repair of programmed DNA lesions in antibody class switch recombination: common and unique features
por: Shang, Yafang, et al.
Publicado: (2021)

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells
por: Pan-Hammarström, Qiang, et al.
Publicado: (2005)

To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks
por: Casari, Erika, et al.
Publicado: (2022)

Immunoglobulin Class Switch Recombination Is Impaired in Atm-deficient Mice
por: Lumsden, Joanne M., et al.
Publicado: (2004)

Connecting by breaking and repairing: mechanisms of DNA strand exchange in meiotic recombination
por: Sansam, Christopher L, et al.
Publicado: (2015)

53BP1 is required for class switch recombination
por: Ward, Irene M., et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_d8j6692htrbr4e2eot32rp1imp