DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination
The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and Artemis are classical nonhomologous DNA end-joining (C-NHEJ) factors required for joining a subset of DNA double-strand breaks (DSB), particularly those requiring end processing. In mature B cells, activation-induced cytidine deaminas...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275379/ https://www.ncbi.nlm.nih.gov/pubmed/18316419 http://dx.doi.org/10.1084/jem.20080044 |