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DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination

The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and Artemis are classical nonhomologous DNA end-joining (C-NHEJ) factors required for joining a subset of DNA double-strand breaks (DSB), particularly those requiring end processing. In mature B cells, activation-induced cytidine deaminas...

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Detalles Bibliográficos
Autores principales:	Franco, Sonia, Murphy, Michael M., Li, Gang, Borjeson, Tiffany, Boboila, Cristian, Alt, Frederick W.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275379/ https://www.ncbi.nlm.nih.gov/pubmed/18316419 http://dx.doi.org/10.1084/jem.20080044

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