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Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates γ irradiation–induced thymic lymphoma development

Members of the Bcl-2 protein family play crucial roles in the maintenance of tissue homeostasis by regulating apoptosis in response to developmental cues or exogenous stress. Proapoptotic BH3-only members of the Bcl-2 family are essential for initiation of cell death, and they function by activating...

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Detalles Bibliográficos
Autores principales: Labi, Verena, Erlacher, Miriam, Kiessling, Stephan, Manzl, Claudia, Frenzel, Anna, O'Reilly, Lorraine, Strasser, Andreas, Villunger, Andreas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275386/
https://www.ncbi.nlm.nih.gov/pubmed/18299399
http://dx.doi.org/10.1084/jem.20071658