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A gammaherpesvirus-secreted activator of Vβ4(+) CD8(+) T cells regulates chronic infection and immunopathology

Little is known about herpesvirus modulation of T cell activation in latently infected individuals or the implications of such for chronic immune disorders. Murine gammaherpesvirus 68 (MHV68) elicits persistent activation of CD8(+) T cells bearing a Vβ4(+) T cell receptor (TCR) by a completely unkno...

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Detalles Bibliográficos
Autores principales: Evans, Andrew G., Moser, Janice M., Krug, Laurie T., Pozharskaya, Veranika, Mora, Ana L., Speck, Samuel H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275388/
https://www.ncbi.nlm.nih.gov/pubmed/18332178
http://dx.doi.org/10.1084/jem.20071135