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Suppression of Leukotriene B(4) Generation by Ex-vivo Neutrophils Isolated from Asthma Patients on Dietary Supplementation with Gammalinolenic Acid-containing Borage Oil: Possible Implication in Asthma

Dietary gammalinolenic acid (GLA), a potent inhibitor of 5-lipoxygenase (5-LOX) and suppressor of leukotriene B(4) (LTB(4)), can attenuate the clinical course of rheumatoid arthritics, with negligible side effects. Since Zileuton, also an inhibitor of 5-LOX, attenuates asthma but with an undesirable...

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Detalles Bibliográficos
Autores principales: Ziboh, Vincent A., Naguwa, Stanley, Vang, Kao, Wineinger, Julie, Morrissey, Brian M., McIntyre, J. A., Watnik, Mitchell, Gershwin, M. Eric
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275406/
https://www.ncbi.nlm.nih.gov/pubmed/15154607
http://dx.doi.org/10.1080/10446670410001670445