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Suppression of Leukotriene B(4) Generation by Ex-vivo Neutrophils Isolated from Asthma Patients on Dietary Supplementation with Gammalinolenic Acid-containing Borage Oil: Possible Implication in Asthma
Dietary gammalinolenic acid (GLA), a potent inhibitor of 5-lipoxygenase (5-LOX) and suppressor of leukotriene B(4) (LTB(4)), can attenuate the clinical course of rheumatoid arthritics, with negligible side effects. Since Zileuton, also an inhibitor of 5-LOX, attenuates asthma but with an undesirable...
Autores principales: | Ziboh, Vincent A., Naguwa, Stanley, Vang, Kao, Wineinger, Julie, Morrissey, Brian M., McIntyre, J. A., Watnik, Mitchell, Gershwin, M. Eric |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275406/ https://www.ncbi.nlm.nih.gov/pubmed/15154607 http://dx.doi.org/10.1080/10446670410001670445 |
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