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The Development of Mouse APECED Models Provides New Insight into the Role of AIRE in Immune Regulation

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy is a rare recessive autoimmune disorder caused by a defect in a single gene called AIRE (autoimmune regulator). Characteristics of this disease include a variable combination of autoimmune endocrine tissue destruction, mucocutaneous cand...

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Detalles Bibliográficos
Autores principales: Pereira, Lara E., Bostik, Pavel, Ansari, Aftab A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275420/
https://www.ncbi.nlm.nih.gov/pubmed/16295527
http://dx.doi.org/10.1080/17402520500212589