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The involvement of FOXO1 in cytotoxic stress and drug-resistance induced by paclitaxel in ovarian cancers

The role of transcriptional factor FOXO1 in the mechanism of drug-resistance in ovarian cancer has not been elucidated. In ovarian cancer cell lines, FOXO1 expression and its correlation with paclitaxel treatment was investigated by cytotoxic assay and silencing experiment. Clinical ovarian cancer s...

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Detalles Bibliográficos
Autores principales: Goto, T, Takano, M, Hirata, J, Tsuda, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275483/
https://www.ncbi.nlm.nih.gov/pubmed/18319717
http://dx.doi.org/10.1038/sj.bjc.6604279