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Structural insight into the TFIIE–TFIIH interaction: TFIIE and p53 share the binding region on TFIIH

RNA polymerase II and general transcription factors (GTFs) assemble on a promoter to form a transcription preinitiation complex (PIC). Among the GTFs, TFIIE recruits TFIIH to complete the PIC formation and regulates enzymatic activities of TFIIH. However, the mode of binding between TFIIE and TFIIH...

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Detalles Bibliográficos
Autores principales: Okuda, Masahiko, Tanaka, Aki, Satoh, Manami, Mizuta, Shoko, Takazawa, Manabu, Ohkuma, Yoshiaki, Nishimura, Yoshifumi
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275666/
https://www.ncbi.nlm.nih.gov/pubmed/18354501
http://dx.doi.org/10.1038/emboj.2008.47