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Pore Mutations of the Escherichia coli MscS Channel Affect Desensitization but Not Ionic Preference

Mechanosensitive channels rescue bacterial cells from a fate of lysis when they transfer from a high- to low-osmolarity environment. Of three Escherichia coli mechanosensitive proteins studied to date, only MscS-Ec demonstrates a small anionic preference and a desensitized, nonconducting state under...

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Detalles Bibliográficos
Autores principales: Edwards, Michelle D., Bartlett, Wendy, Booth, Ian R.
Formato: Texto
Lenguaje:English
Publicado: The Biophysical Society 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275705/
https://www.ncbi.nlm.nih.gov/pubmed/18065458
http://dx.doi.org/10.1529/biophysj.107.123448