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Sequence variation in the human transcription factor gene POU5F1
BACKGROUND: POU5F1 expression is required to maintain stem cell pluripotency and for primordial germ cells to retain proliferative capability in embryonic development. Recent evidence suggests that POU5F1 may also be a testicular germ cell carcinoma (TGCC) oncogene, and POU5F1 variation may influenc...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275747/ https://www.ncbi.nlm.nih.gov/pubmed/18254969 http://dx.doi.org/10.1186/1471-2156-9-15 |