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Sequence variation in the human transcription factor gene POU5F1

BACKGROUND: POU5F1 expression is required to maintain stem cell pluripotency and for primordial germ cells to retain proliferative capability in embryonic development. Recent evidence suggests that POU5F1 may also be a testicular germ cell carcinoma (TGCC) oncogene, and POU5F1 variation may influenc...

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Detalles Bibliográficos
Autores principales:	Hussain, Shehnaz K, Sequerra, Reynaldo, Bertucci, Caterina, Hastings, Noel C, Rieder, Mark, Schwartz, Stephen M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275747/ https://www.ncbi.nlm.nih.gov/pubmed/18254969 http://dx.doi.org/10.1186/1471-2156-9-15

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