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Protective Effects of Coenzyme Q(10) on Decreased Oxidative Stress Resistance Induced by Simvastatin

The effects of simvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl CoA reductase (HMG-CoA reductase), on oxidative stress resistance and the protective effects of coenzyme Q (CoQ) were investigated. When simvastatin was administered orally to mice, the levels of oxidized and reduced CoQ(9) and C...

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Detalles Bibliográficos
Autores principales: Kettawan, Aikkarach, Takahashi, Takayuki, Kongkachuichai, Ratchanee, Charoenkiatkul, Somsri, Kishi, Takeo, Okamoto, Tadashi
Formato: Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275764/
https://www.ncbi.nlm.nih.gov/pubmed/18398496
http://dx.doi.org/10.3164/jcbn.40.194